Somatotropin (other names: STH, somatotropic hormone, somatropin, growth hormone) is a peptide structure synthesized in the pituitary gland under the influence of certain impulses. This substance regulates the development processes of the whole body, it takes an important part in metabolism, strengthens bones, stimulates the acceleration of growth. STH has an impact on the growth of bones in length, and therefore it is so necessary for the human body. Below we will take a closer look at what growth hormone is and its main features. What amount of somatotropic hormone is contained in the blood? The production of STH is carried out throughout human life cyclically. Its concentration in the blood seriously depends on age, for example, in children under 3 years of age it is maximum. At 20 years of age, it decreases by 50 percent, but the hormone’s production is still quite high. But after reaching the age of 30, the production of the substance decreases, and its concentration remains at approximately the same level. As a consequence, aging processes are triggered, and immunity decreases slightly. Upon reaching the age of forty-five, the pituitary gland synthesizes half as much STH as in the past years. The body continues to age and it becomes visible. Sleeping problems occur, appetite worsens, and overweight appears. Also, the amount of STH in the blood depends on the time of day. At night, about one or two hours after the beginning of sleep, the hormone is produced more, because that is when the peak of its work on stimulation of human growth begins. During the daytime, the amount decreases, but periodically, every four or five hours, there are sharp rises in the level of STH. In men, the concentration of the hormone averages from 1 to 5 µg / l, and in women from 0 to 17 µg / l. In old age, in men it decreases usually to 2 µg / l, and in women it does not exceed 10-15 µg / l. How to establish the level of STH? Scientists have found out what growth hormone is and that it is synthesized in cycles. Therefore, it is necessary to know at what time to analyze its concentration in the blood. In simple polyclinics, conducting such a study is not provided, so it is possible to detect the level of STH only in a specialized laboratory. To find out the concentration of somatropin, it is necessary to analyze venous blood. From other tests, it differs in that a week before the procedure, the patient must undergo radiographic examination. Blood should be taken on an empty stomach, the day before not eating fatty and sweet foods, as well as alcoholic beverages. Before the test, it is better to stop smoking. If you use any medications, you need to warn your doctor about it. How and where somatotropic hormone is produced The synthesis of STH is carried out in the pituitary gland, by cells that are called somatotropins. Growth hormone is so called because this substance is most produced during adolescence, when the body develops rapidly. Children actually grow when they sleep, as there is a surge in somatotropin synthesis one to two hours after falling asleep.

Somatotropin is synthesized at the expense of somatoliberin, while somatostatin, on the other hand, prevents its production. The synthesis of somatotropin is carried out in the following way – the hypothalamus sends a signal to the pituitary gland, after which it begins to produce the hormone. Then the growth hormone is in the blood and together with it is sent to the liver. In the liver cells it is converted into another substance called somatomedin. This substance is what goes into the muscle cells throughout the body. Functions and useful properties of the hormone The hormone somatotropin indirectly or directly affects almost all processes in the human body. First of all, it stimulates the growth of the skeleton and soft tissues, strengthens the bone system, as well as muscles and tissues of the body. In addition, human growth hormone acts as follows: regulates the content of cholesterol, the lack of which can adversely affect the cardiovascular system, takes part in the production of collagen, responsible for the state of the dermis and provides connective tissues strength and elasticity. If there is a lack of collagen, the skin ages faster; participates in the breakdown of fats at night during sleep. If this mechanism is disrupted, extra pounds will quickly be added; lengthens bones and adds strength to them, which is very important during adolescence. This is due to the fact that growth hormones are involved in the production of vitamin D3, which depends on how strong the bones will be, has a beneficial effect on the body, energizes it, provides normal sleep and good mood, reduces the percentage of subcutaneous fat. prevents the destruction of muscle, which occurs with heavy physical exertion, especially if there is not enough protein and carbohydrates, regulates the metabolism of carbohydrates. The hormone somatotropin acts as an opponent of insulin, that is, works opposite to it, preventing the use of glucose in tissues; has an immunostimulant effect. The hormone activates the immune system cells, accelerates the growth of young people, as well as accelerates the healing of wounds and restoration of tissues affected, activates the growth of cartilage, promotes the formation of breast milk in lactating women. Also somatotropin strengthens the immune system, has an effect on calcium metabolism. With the help of a synthetic hormone, you can build muscle mass, so it is considered a doping and is prohibited for use by athletes. STH affects the synthesis of IGF1 protein in the liver. The protein, in the functions it performs, resembles insulin. Reduced levels of STH Hypophyseal nanism Insufficient amounts of somatotropin in children are mainly due to genetic defects and become the cause of delayed growth, and in some cases puberty and general physical development. With a deficiency of the hormone in boys, underdeveloped muscles, pale skin, high timbre of voice, enlargement of the breast glands, the appearance of fatty deposits, which are characteristic of women. Symptoms of STH deficiency in girls are the same, except for breast glands, which on the contrary do not grow. Also, girls have delayed menstruation, which usually appears before the age of fifteen. On the pubic area and armpits in these children do not grow hair. Lack of hormone occurs due to various reasons, such as violations of the hormonal background, heredity, heavy pregnancy. Low levels of somatotropin in adults negatively affects metabolism and provokes increased deposition of fat in the body. At the same time, a variety of diseases of the endocrine system often develop. STH deficiency can be provoked by taking some medical drugs, as well as the use of chemotherapy. In some cases, somatotropin deficiency is caused by high blood sugar, high concentration of free fatty acids in the blood, as well as the hormone somatostatin, which inhibits the production of pituitary STH.
Lack of this substance adversely affects the general tone and nervous system, resulting in increased irritability and even depression. Deficiency of the hormone is often accompanied by such a disease as pituitary nanism. People suffering from this pathology undeveloped skeleton and internal organs, so they have a very low growth – in males the growth does not exceed one hundred thirty centimeters, and in females it is an average of 120 centimeters. To reduce the risk of STH deficiency, children need a proper balanced diet. It is very important in what environment the child lives. Experts believe that this condition is observed more often in children from bad families. When getting into a favorable environment, the production of STH normalizes. Elevated levels of STH Acromegaly An excess of somatotropin affects the body of children and adults in different ways. Children with an increased content of this hormone suffer from gigantism – have a very high growth, which significantly exceeds the growth of peers. Their hands and feet become significantly larger, the shape of the face changes greatly, especially the nose and jaw, which increase in size. Such changes are correctable, but this requires prolonged treatment under the supervision of a doctor. With gigantism, the functioning of internal organs is disturbed, which leads to early death. High levels of STH can be due to the presence of a malignant or benign neoplasm in the pituitary gland. It also occurs against the background of renal failure, a defect in the receptors that respond to growth hormone, diabetes mellitus, excessive consumption of alcohol-containing beverages, stomach and lung tumors. People over the age of twenty-five do not grow in length because somatoliberin has a limiting effect. For this reason, when they have an overabundance of the hormone, their bones begin to grow in width. Such pathology is called acromegaly. Patients who suffer from it have a very wide nose, large hands and feet, enlarged nose and ears. Acromegaly is an extremely dangerous disease. The disfigurement is not yet the worst, since the face can be changed with the help of plastic surgery. But in addition, patients often have disorders in the cardiovascular system, increases insulin insensitivity, which leads to type 2 diabetes, compressed nerves. In addition, elevated levels of STH causes tunnel syndrome – patients have numb fingers and hands, and joints unpleasant tingling. Signs are manifested as a result of nerve trunk compression. Overabundance of STH causes the development of tissue resistance to insulin. Because of this, sugar is not able to penetrate from the blood into the cells and the insulin content constantly exceeds the norm, which leads to a sharp weight gain. This is accompanied by high blood pressure and swelling. Somatotropic hormone preparations When the level of STH decreases, drugs based on somatotropin are taken. The duration of the treatment course with such means can be several years. They should be prescribed only by a doctor after a complete examination of the patient. Drugs differ in the way they are obtained. Previously, the substance was extracted from human corpses, but today it is synthesized artificially. The best quality means are considered to be those obtained through genetic engineering. In particular, they use a drug called Somatropin, which allows you to increase the concentration of the hormone in the blood. Its release is carried out in the form of a white powder. First it is dissolved with water, and then injected into the body. The drug is also released in the form of tablets, which are mainly used as a supplement for rapid muscle growth. But it is recommended to use only the powder, since tablets are very often counterfeited. Thanks to this remedy, muscle mass increases in a short period of time. It is prescribed to children with retarded development and growth, not appropriate for age and adolescents, with the presence of kidney failure. Adults are prescribed the drug if somatotropic hormone is produced in insufficient quantities, due to certain disorders. The drug should not be taken by pregnant or breastfeeding women, patients with cancerous tumors and brain injury. Somatropin can cause side effects increased blood pressure; migraine; thyroid disease; and edema. There is a possibility of hypothyroidism when using STH-based drugs, which is why they should only be taken under the supervision of a specialist. Somatrem is another well-known drug based on somatropin. With its help, it is used to treat disorders of the nervous system, eliminate growth problems in children, reduce fat layer and build muscle. The drug is also used for prophylactic purposes, to prevent the development of senile diseases. The hormone somatotropin has a rejuvenating effect on the body of the elderly, as a result, wrinkles are smoothed out and the skin becomes elastic. Somatrem is not allowed to be used by professional athletes. If there is a suspicion of STH deficiency, therapy should be started immediately. Otherwise, it is possible to develop infertility or weakening of the heart muscle, which is fatal.

Somatotropin in Sports Due to somatotropin’s ability to affect muscle fiber growth, it has come to be used by athletes in a variety of sports. Some studies suggest that the hormone’s ability to affect strength and endurance is low. But despite this, growth hormones are actively used to build muscle and reduce fat layer (to achieve a pronounced relief). For these purposes, the medical instructions for use (to compensate for the deficiency of its own hormone) are not suitable. In sports, higher dosages are used, greatly exceeding the therapeutic dosages. These achieve excessive stimulation of muscle cells, which leads to the desired result. In addition to the basic rules for the use of drugs, in bodybuilding there are several other points: for a beginner, the dosage should not exceed 4-5 units per day; the drug is started with small amounts, gradually bringing the dose to the required values; training mainly includes weight-bearing exercises with weights and high-intensity sports; the duration of exercise should be at least 1-1.5 hours with a frequency of 4-5 times a week; the composition of the diet is possible with the inclusion of specialized sports nutrition. HGH Somatropin Growth hormone preparations are represented by two groups: products registered in Russia for medical use; products manufactured exclusively for use in the world of bodybuilding, which have not been registered on the Russian pharmaceutical market. The second group is the most widespread among athletes, as it does not require a prescription from a doctor. These drugs are produced abroad and their supply to the country is illegal. Among them there are their favorites, which are considered the best. The most positive reviews received: HGH Somatropin amino acid 191 10vials x 10iu from GenoPharm ; Canada Peptides Somatropin 191aa 10 IU . These products are of high quality, which is why they have virtually no negative reviews.

Somatotropin in bodybuilding The main reasons for the popularity of somatotropin in bodybuilding are several. of them – the desire to get rid of subcutaneous fat, especially during “drying”. Also stimulation of the growth of dry muscle fibers, connective tissues and increase the volume of muscle mass cells. An important advantage is the minimal risk of injuries and sprains due to the strengthening of tendons and cartilage. Thanks to the production of the hormone in the body, a beautiful relief of muscles is drawn. Despite the misconceptions of many, the hormone does not affect the performance and endurance of athletes, nor does it increase strength! A clear advantage of somatotropin over steroidal drugs is the absence of negative effects on potency and other important systems of the human body. Medical preparation Somatotropin is a highly effective substitute for the natural hormone, if it is not possible or sufficient to achieve its increase naturally. This supplement is a creation of genetic engineering, contains no prohibited components and fully complies with all the norms of anti-doping rules. The drug is suitable for both beginners and experienced bodybuilders. In addition to the positive properties of its natural counterpart has a number of additional useful functions: Reduces cholesterol levels. Improves the work of the heart muscle. Stimulates the synthesis of collagen. Strengthens the processes of glycogenesis. Promotes the production of endorphins. Improves mental abilities. Increases sexual activity. Improves the lipid state of the skin. Beneficial effect on the nervous system. The effectiveness of the drug to fight obesity, slow aging and build muscle is proven by millions of consumers and scientific studies. It is important to know how to take somatotropin, and strictly follow the prescriptions, because it is not ascorbic acid, which is “crunched” like candy. If the dosage is incorrect, there will inevitably be negative consequences. Among the most difficult side effects is the development of diabetes, hypertension, sleep disorders and acromegaly. But all of this can only occur with prolonged, large overdose. One of the main, and very significant disadvantages of growth hormone preparations is their high cost, and the course should last at least 3-4 weeks, optimally 3 months. Expensive due to the complex processes that are needed for its production. For example, earlier manufacturers extracted growth hormone from cadavers for quite a long time, but in 1989 its use was banned by the Olympic Committee. For many years, it was sold illegally. Today, the drug is recombinant, authorized and completely safe to use. An experienced sports doctor will help you develop a regimen, taking into account your individual data, type of sport and severity of loads. The higher they are, the higher the dose will be required. The injection should be injected strictly according to the rules, observing sterility. The duration of the course is about 3 months, during this time the body will have time to get used to the drug and the effect will decrease. After that, it is necessary to make a break equal to the time of use. The main rule when taking it is to observe a strict regimen, follow the rules of a balanced diet and physical activity. Each workout, meal and drug intake should be done strictly according to the schedule, otherwise the result will not be or it will be less pronounced.